By Barry Behr, PhD, HCLD Introduction Preimplantation genetic diagnosis (PGD) and screening (PGS) refer to the procedures involved in obtaining genetic makeup of the embryo(s) prior to their transfer into the uterus. Genetic errors arise from deletions or insertions of genetic material, abnormal numbers of whole chromosomes or genes, and even from misplacement of a...
Category: Physicians Published Articles
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Preserving Reproductive Options in Oncology Patients
By Bradford Kolb, MD, FACOG Board Certified, Reproductive Endocrinology and Infertility Introduction Over the last several decades we have witnessed a significant increase in survival rates for oncology patients. Due to the use of combination chemotherapy and radiotherapy many young patients are now living long, healthy, productive lives. While combination regimens have been designed to...
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The Contemporary Fertility Evaluation
By Daniel Potter, MD, FACOG Board Certified, Reproductive Endocrinology and Infertility Introduction Infertility is a complex medical, emotional and social condition that afflicts more than four million reproductive-age couples in the United States. Successful fertility treatment includes not only achieving pregnancy, but also achieving it in the most efficient and cost effective manner possible. The...
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Third Party Parenting
By Michael Feinman, MD, FACOG Board Certified, Reproductive Endocrinology and Infertility Since the very first IVF procedure, the theoretical ability to perform egg donation or gestational surrogacy has existed. It took doctors and society a few years to realize this fact and embrace the concept. Considering the wide variation in the legal status of egg...
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Treatment Options for Those Who have Failed Assisted Reproductive Technologies
By Bradford Kolb, MD, FACOG Board Certified, Reproductive Endocrinology and Infertility Reproductive medicine has expanded treatment options to many who would otherwise not be able to have children. Despite these advances, many still experience challenges and the emotional distress of unsuccessful treatment. While some continue treatment, others succumb to these stresses and give up pursuing...
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What to do with Frozen Embryos
by Jane L. Frederick, MD, FACOG Board Certified, Reproductive Endocrinology and Infertility Couples going through infertility have many decisions to make. For couples who have gone through in-vitro fertilization (IVF) and have extra frozen embryos which they no longer need, the decision of what to do with their frozen embryos is difficult. They can choose...
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Assisted Hatching
By Jeffrey Nelson, DO, FACOOG There are a multitude of factors contributing to a couple’s inability to conceive, including male factor, uterine factor, tubal factor, pelvic factor, and ovulatory dysfunction. The majority of these factors can be circumvented through the application of advanced reproductive treatments like in-vitro fertilization (IVF). The success of IVF depends on...
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Alternatives For Ovulation Induction and Superovulation: SERMs and Aromatase Inhibitors
By David E. Tourgeman MD, FACOG Board Certified, Reproductive Endocrinology and Infertility Introduction Ovulatory dysfunction is one of the most common causes for reproductive difficulty in otherwise fertile couples. Once successful ovulation is achieved, fertility is often restored. For many years, the first line of pharmacologic ovulation induction has involved the use of selective estrogen...
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