Meet Dr. Botros Rizk, MD, FACOG
HRC Fertility Pasadena is proud to welcome Dr. Botros Rizk, MD, FACOG to our group of award winning physicians.
Dr Botros Rizk is a world renowned Reproductive Endocrinology and Infertility Specialist practicing at our Pasadena office. He is a pioneer in the field of reproductive medicine and infertility. He is also professor of Obstetrics and Gynecology and the chief of the REI division at the USC Keck School of Medicine. Dr Rizk started his medical career at Cairo University School of Medicine where he graduated and then he went to complete his prestigious fellowship at The Bourn Hall Clinic in London and Cambridge, UK and joined the University of Cambridge as Clinical lecturer and Senior Registrar. Dr Rizk has an international following of patients from Dubai, Qatar, Egypt and Saudi seeking guidance and precision.
Mentored by Nobel Laureate Professor Robert Edwards, recipient of the Nobel prize in Medicine for achieving the first successful in vitro fertilization in the world, Dr. Rizk started his career in reproductive medicine in London and Cambridge in the era where most of the current scientific developments and medical protocols were invented. Dr Rizk is also one of the early members of European Society for Human Reproduction and Embryology (ESHRE) and a founding member and former president of Middle East Fertility Society (MEFS). Dr Rizk worked daily with the legendary trio professors Stuart Campbell, Howard Jacobs and Robert Edwards. Dr Rizk was Chair of the ASRM international membership committee linking ASRM, ESHRE, and MEFS for seven years. He was also the secretary and representative of the Royal College in London (RCOG) to the American College of Obstetrics and Gynecology (ACOG) for six years.
Dr. Rizk is board certified in Obstetrics and Gynecology by the American Board of Obstetrics and Gynecology, the Royal College of Physicians and Surgeons of Canada, the Royal College of Obstetricians and Gynecologists in England, and the American Board of Bioanalysts in Embryology and Andrology. He has edited and authored twenty eight medical textbooks and more than four hundred manuscripts embracing different aspects of infertility and assisted reproduction as well as ultrasonography and robotic surgery. Dr Rizk reported the world’s first 1,000 IVF babies from Bourn Hall Clinic in a landmark publication that settled early concerns about IVF babies.
Dr. Rizk’s clinical and research interests have focused on ovarian stimulation including the development of the long agonist protocol which became the standard for two decades of IVF. He is internationally considered a leading authority on ovarian hyperstimulation syndrome and made original contributions to the pathophysiology and prevention of the syndrome. Dr. Rizk authored a book dedicated to ovarian hyperstimulation syndrome that is considered the standard reference for OHSS. He is also the principal investigator for tens of clinical trials for the FDA over the last three decades for infertility, osteoporosis, menopause, and decreased libido while he was a tenured professor of obstetrics and gynecology at the University of S Alabama and medical director of Elite IVF in Houston.
When he is not practicing medicine, Dr Rizk enjoys traveling with his family. He has traveled to 70 countries all over the world. He also enjoys playing piano, tennis and swimming as well as spending time listening to Oriental music and visiting the beach.
Upcoming Events
March 2026
3/11/2026: Free Egg Freezing Webinar with Dr. Alison Peck
3/11/2026: Free Fertility 101 Seminar with Dr. John Norian
3/24/2026 Webinar – “Egg Freezing 101” with Dr. Mickey Coffler
3/24/2026: Free AMH Testing Event With Dr. VanHise at HRC Fertility Beverly Hills
3/25/2026: Free Fertility 101 Lunch Webinar with Dr. Sasha Hakman
3/25/2026: Free AMH Testing Event With Dr. Handelsman at HRC Fertility Westlake Village
3/26/2026: Join Dr. Michael Wittenberger for a Free AMH Testing at HRC Fertility San Diego
April 2026
4/21/2026: AMH Testing Event During Infertility Awareness Week with Dr. Mickey Coffler
Medical School: Cairo University School of Medicine
Fellowship: The Bourn Hall Clinic in London and Cambridge, UK
Residency: Farnborough Hospital, Kent England
- American Association of Bioanalysts (AAB)
- American College of Obstetrics and Gynecology (ACOG)
- American Society of Reproductive Medicine (ASRM)
- American College of Surgeons (ACS)
- European Society for Human Reproduction and Embryology (ESHRE)
- Middle East Fertility Society (MEFS)
- Royal College in London (RCOG)
Honors and Awards:
- The American Association of Gynecologic Laparoscopists, Certificate of Special Excellence in Endoscopy
- ACOG American College of Obstetrics and Gynecology – Zeneca Award Prize Winning Paper
- American society for reproductive medicine ASRM Gold service award 2019
- Top doctors in America Castle Connolly 2017
- Best teacher of the year university of South Alabama 1998
Dr. Rizk’s clinical and research interests have focused on ovarian stimulation including the development of the long agonist protocol which became the standard for two decades of IVF. He is internationally considered a leading authority on ovarian hyperstimulation syndrome and made original contributions to the pathophysiology and prevention of the syndrome.
Dr. Rizk authored a book dedicated to ovarian hyperstimulation syndrome that is considered the standard reference for OHSS. He is also the principal investigator for tens of clinical trials for the FDA over the last three decades for infertility, osteoporosis, menopause, and decreased libido while he was a tenured professor of obstetrics and gynecology at the University of S Alabama and medical director of Elite IVF in Houston.
Published Manuscripts:
- Ovarian cyst aspiration and the outcome of in-vitro fertilization
B Rizk, SL Tan, CR Kingsland, C Steer, BA Mason, S Campbell
Fertility and Sterility 1990; 54(4): 661-664. - Severe ovarian hyperstimulation syndrome and cerebrovascular accidents
B Rizk, S Meagher, AM Fisher
Human Reproduction 1990; 5(6): 697-698. - Ovarian hyperstimulation presenting as acute hydrothorax after in-vitro fertilization
CR Kingsland, JV Collins, B Rizk, BA Mason
American Journal of Obstetrics Gynecology 1989; 161: 381-382. - Sex ratio and in-vitro fertilization
C Steer, SL Tan, B Rizk, P Brinsden, BA Mason, S Campbell
The Lancet, 2(8667): 863. - Conception rates and in-vitro fertilization
SL Tan, CV Steer, P Royston, B Rizk, BA Mason, S Campbell
The Lancet 1990; 335: 299-230. - Rare ectopic pregnancies after in-vitro fertilization: One unilateral twin and four Bilateral tubal pregnancies
B Rizk, S Morcos, S Avery, K Elder, P Brinsden, BA Mason, RG Edwards
Hum Reprod 1990; 5(8): 1025-1028. - Ovarian pregnancy following in-vitro fertilization and embryo transfer
B Rizk, GCL Lachelin, MC Davies, GM Hartshorne, RG Edwards
Hum Reprod 1990; 5(6): 763-764. - Prevalence of multiple pregnancies associated with the use of GnRH analog in IVF
CR Kingsland, SL Tan, N Bickerton, B Rizk, CV Steer, S Avery, BA Mason, S Campbell
Assisted Reproductive Technology/Andrology 1990; 1: 76-80. - Is the routine administration of a short course of buserelin useful in-vitro fertilization? A prospective randomized study
CR Kingsland, SL Tan, N Bickerton, B Rizk, C Steer, C Mills, N White, S Smith,
BA Mason, S Campbell
Assisted Reproductive Technology/Andrology 1990;1: 287-291. - Heterotopic pregnancies following in-vitro fertilization and embryo transfer
B Rizk, SL Tan, S Morcos, A Riddle, P Brinsden, BA Mason, RG Edwards
American J of Obstetrics and Gynecology 1991;164(1):161-164. - Edwards syndrome after the replacement of cryopreserved thawed embryos
B Rizk, RG Edwards, U Nicolini, S Meagher, RF Lamont
Fertility and Sterility 1991; 55(1): 208-210. - Improvement of spontaneous pregnancy rate after stopping gonadotropin therapy for anovulatory infertility
MA Aboulghar, RT Mansour, GI Serour, B Rizk, R Riad
Fertility and Sterility 1991; 55: 722-725. - Modern management of ovarian hyperstimulation syndrome
B Rizk, M Aboulghar
Human Reproduction 1991; 6(8): 1082-1087. - Perinatal outcome and congenital malformations in in-vitro fertilization babies from the Bourn Hallam Group
B Rizk, P Doyle, SL Tan, PA Rainsbury, J Betts, P Brinsden, RG Edwards
Human Reproduction 1991; 6(9): 1259-1264. - Ultrasonic transvaginal aspiration of endometriotic cysts: an optional line of treatment in selected cases of endometriosis
MA Aboulghar, RT Mansour, GI Serour, B Rizk
Human Reproduction 1991; 6(10): 1408-1410. - Ovarian hyperstimulation syndrome after superovulation using GnRH agonists for IVF and related procedures
B Rizk, J Smitz
Human Reproduction 1992; 7(3): 320-327. - Immunohistochemical expression of endometrial proteins and pregnancy outcome in frozen embryo replacement cycles
B Rizk, CV Manners, MC Davies, CV Steer, SC Bell, D Dillon, RG Edwards
Human Reproduction 1992; 7(3): 413-417. - Rupture of membranes prior to the onset of spontaneous labor increases the likelihood of instrumental delivery
AS Kong, SJ Bates, B Rizk
British J of Anesthesia 1992; 68(3): 252-255. - Obstetric outcome of in-vitro fertilization pregnancies compared to naturally conceived pregnancies
SL Tan, P Doyle, S Campbell, V Beral, B Rizk, P Brinsden, BA Mason, RG Edwards
American Journal of Obstetrics and Gynecology 1992; 167(3):778-784. - Ectopic pregnancy: epidemiology, advances in diagnosis and management
ES Dimitry, B Rizk
British Journal of Clinical Practice 1992; 46(1): 52-54. - The obstetric outcome of assisted conception treatment
PR Brinsden, B Rizk
Assisted Reproduction Reviews 1992; 2: 16-25. - Intrauterine replacement of oocytes with bound sperms
B Rizk
Fertility, Sterility and Contraception 1993; I: 201-208. - In vitro survival of spermatozoa in the human fallopian tube for 25 days: a case report
RT Mansour, MA Aboulghar, GI Serour, AM Abbas, AM Ramzy, B Rizk
Journal of Assisted Reproduction and Genetics 1993; 10(5): 379-380. - Tuberculous infertility and in vitro fertilization
SF Marcos, B Rizk, S Fountain, PR Brinsden
American Journal of Obstetrics and Gynecology 1994; 171(6): 1593-1596. - Gamete intrafallopian transfer in patients with pelvic endometriosis
B Rizk, S Aksel, A Helvacioglu
Gynecology, Obstetrics and Reproductive Medicine 1995; 1: 124-126. - Sexual dysfunction and its management in the gynecological cancer patient
B Rizk, KC Brewington, IH Thorneycroft
The Journal of Clinical Practice in Sexuality 1995; 10, I/II: 26-29. - Managing oral contraception users who smoke
B Rizk, IH Thorneycroft
The Journal of Clinical Practice in Sexuality 1995: 10, III/IV: 34-42. - Successful use of pentoxifylline in male factor infertility and previous failure of fertilization in-vitro: a prospective randomized study
B Rizk, S Fountain, S Avery, C Palmer, M Blayney, M Macnamee, C Mills, PR Brinsden
Journal of Assisted Reproduction and Genetics 1995; 12(10): 710-714. - An evaluation of the effect of pentoxifylline on sperm function and treatment outcome of male factor infertility; a preliminary study
S Fountain, B Rizk, S Avery, C Palmer, M Blayney, M Macnamee, C Mills,
PR Brinsden
Journal of Assisted Reproduction and Genetics 1995; 12(10): 704-709. - Reproductive risks of cocaine
B Rizk, JL Atterbury, LJ Groome
Human Reproduction Update 1996; 2(1): 43-55. - Calcified pelvic mass in a 75 year old woman
B Rizk, BA Georgy, JD West, DB Safran, BG Brogdon
Academic Radiology 1996; 3(2): 165-169. - Ovarian hyperstimulation syndrome: Modern concepts in pathophysiology and management
MA Aboulghar, RT Mansour, GI Serour, B Rizk
Middle East Fertility Society Journal 1996; 1(1): 3-16. - Effects of human serum albumin sources on sperm wash and intrauterine insemination results
RR Yeoman, CA Huff, A Helvacioglu, S Aksel, B Rizk
Middle East Fertility Society Journal 1996; 1(1): 41-43. - Deletion of long arm of the X chromosome (46 XX q21) in a patient with primary amenorrhea:
Is there a correlation between the Karyotype and the Phenotype?
B Rizk, L Royster, IH Thorneycroft, RR Yeoman, J Martinez, JC Warren
Middle East Fertility Society Journal 1996; 1(1): 83-85. - Human sperm bioassay has potential in evaluating quality of cumulus-oocyte complexes
AM Hossain, B Rizk, C Huff, A Helvacioglu, IH Thorneycroft
Archives of Andrology 1996; 37:7-10. - The role of operative laparoscopy in the treatment of tubo-ovarian abscesses
B Rizk, IH Thorneycroft
The Female Patient 1996; 21: 76-77. - Fractions of Percoll eliminated sperm: increased sperm yield in Percoll wash
AM Hossain, C Huff, B Rizk
Arch Androl 1996; 37: 189-195. - A microscopic approach of sperm preparation for intracytoplasmic sperm injection (ICSI)
A Hossain, S Barik, B Rizk, IH Thorneycroft
Middle East Fertility Society Journal 1996; 1(2): 146-150. - The impact of pelvic inflammatory disease and tubal damage on heterotopic pregnancy following in vitro fertilization and embryo transfer
B Rizk
The Journal of Clinical Practice in Sexuality 1996; 11(3/4): 46-51. - Female chronological age determines the implantation rate after intracytoplasmic Sperm injection
I El-Danasouri, E Chung, E Kemmann, B Rizk
Middle East Fertility Society Journal 1996; 1(3): 217-222. - Diamond-Blackfan anemia following in vitro fertilization
B Rizk, SL Baker, LJ Groome
Middle East Fertility Society Journal 1996; 1(3): 243-245. - Cumulus-oocyte complex: Human sperm bioassay
AM Hossain, B Rizk, C Huff, A Helvacioglu, IH Thorneycroft
Assisted Reproduction Technology/Andrology 1996; 7:132-134. - Counseling HIV patients pursuing infertility investigation and treatment
B Rizk, SR Dill
Hum Reprod 1997; 12(3): 415-416. - Absence of flow in ovarian vein: by time-of-flight magnetic resonance
Angiography without evidence of thrombosis
B Rizk, B Georgy, R Snow, S Lynn, IH Thorneycroft
Clinical Imaging 1997; 21: 203-206. - Assessment of the relationship of sperm morphology with seminal and other clinical conditions of semen donors
A Hossain, D Bhaumik, R Selukar, C Huff, B Rizk, IH Thorneycroft
Arch Androl 1997; 39(2): 111-117. - Assessment quality of frozen serum by spectrophotometric analysis and sperm bioassay.
AM Hossain, S Barik, B Rizk, IH Thorneycroft
Arch Androl 1997; 39(2): 119-125. - Outpatient endometrial biopsy
B Rizk, S Youssif, M Ragheb, J Smitz, A Kirolos, S Saleeb
Middle East Fertility Society Journal 1997; 2(2): 102-108. - Hormone replacement therapy in breast cancer survivors
B Rizk
Middle East Fertility Society Journal 1997; 2(2): 112-114. - A novel classification for conscious pain mapping
O Almeida, J Val-Gallas, B Rizk
The Egyptian Journal of Fertility and Sterility 1997; 1: 53-58. - The role of vascular endothelial growth factor and interleukins in the pathogenesis Of severe ovarian hyperstimulation syndrome
B Rizk, M Aboulghar, J Smitz, R Ron-El
Hum Reprod Update 1997; 3(3): 255-266. - Modified guanidinium thiocyanate method for human sperm DNA extraction
AM Hossain, B Rizk, A Behzadian, IH Thorneycroft
Molecular Human Reproduction 1997; 3(11): 953-956. - Evidence for nitric oxide regulation of hamster sperm hyperactivation
RR Yeoman, WD Jones, B Rizk
Journal of Andrology 1998; 19(1): 58-64. - Preconceptional sex selection: past, present and future
AM Hossain, S Barik, B Rizk, IH Thorneycroft
Archives of Andrology 1998; 40(1): 3-14. - Appendectomy under local anesthesia following conscious pain mapping: A report of two cases
OD Almeida, JM Val-Gallas, B Rizk
Human Reproduction 1998; 13 (3): 588-590. - Third generation progestogens and venous thromboembolism
B Rizk
Middle East Fertility Society Journal 1998; 3(2): 114-118. - Time course of hypo osmotic swellings of human spermatozoa: evidence of ordered transition between swelling sub-types.
AM Hossain, B Rizk, S Barik, C Huff, IH Thorneycroft
Human Reproduction 1998; 13 (6): 1578-1583. - Penile vibratory stimulation yields increased sperm and accessory gland production compared to rectal electro ejaculation in an intact primate (Saimiri boliviensis).
RR Yeoman, J Sonksen, S Gibson, B Rizk, CR Abee
Human Reproduction 1998; 13(9): 2527-2531. - Microlaparoscopic ovarian drilling under local anesthesia: A case report
OD Almeida Jr., B Rizk
Middle East Fertility Society Journal 1998; 3(2): 189-191. - Microlaparoscopy: It’s evolution, present and future.
OD Almeida Jr., B Rizk
Middle East Fertility Society Journal 1998; 3(3): 286-287. - Elevated ovarian expression and serum concentration of alpha inhibin in the uteal phase during follicular development in the squirrel monkey (Saimiri boliviensis) compared to the human.
RR Yeoman, LM Crews, DB Zimmer, KD Dahl, B Rizk, CR Abee
Am J Primat 1999; 47(2): 165-179. - Analysis of In Vitro Migration Patterns of Human Spermatozoa by a petri dish-based horizontal column
AM Hossain, S Barik, P Kulkarni, B Rizk
Biology of Reproduction 1999; 61(2): 406-410. - Resistant unilateral hydrothorax as the sole manifestation of ovarian Hyperstimulation syndrome.
L Gore, MG Nawar, Y Rezk, H Chehata, M Abuzeid, M Ashraf, B Rizk
Middle East Fertility Society Journal 2002; 7(2):149-153. - Normal pregnancy outcome after inadvertent long-term exposure to gonadotropin Releasing hormone agonist.
M Abdel-Hamid, Y Rezk, MG Nawar, E Formentini, H Chehata, M Abuzeid, B Rizk.
Middle East Fertility Society Journal 2002; 7(3):237:241. - The Women’s Health Initiative: clinical perspectives
B Rizk
Middle East Fertility Society Journal 2003; 8(1):1-9. - Outcome of inadvertent administration of a gonadotropin-releasing hormone agonist in early pregnancy.
M Sasy, A Abdel-Fattah, B Rizk, M I Abuzeid.
Middle East Fertility Society Journal 2003; 8(2):139-142. - Effect of glutamine on preimplantation mouse embryo development in vitro.
Y Rezk, C Huff, B Rizk.
American Journal Obstetrics and Gynecology 2004, 190:1450-1454. - Genetics of ovarian hyperstimulation syndrome
B Rizk
Reproductive BioMedicine Online 2009; 19(1): 14-27. - Ovarian malposition – mullerian anomalies revisited
A Helvacioglu, S Gilmore, W Wilson, B Rizk
Middle East Fertility Journal, 2010; 15(2):115-118. - Prevention and management of ovarian hyperstimulation syndrome
B Rizk, C Rizk
Current Women’s Health Review, 2010; 6(2):130-145. - Hereditary female cancers: breast, ovarian, and endometrial
M Tucker III, B Rizk
Middle East Fertility Society Journal, 2011; 16(4):241-247. - Controlled ovarian stimulation in difficult cases
S Badawy, B Rizk
Sexuality, Reproduction & Menopause Journal, 2011; 9(2):17-23. - Challenges in the diagnosis and management of interstitial and cornual ectopic pregnancies
B Rizk, C Holliday, M Abuzeid
Middle East Fertility Society Journal, December 2013. 18(4):235-240. - Cervical and cesarean scar ectopic pregnancies: diagnosis and management
B Rizk, C Holliday, S Owens, M Abuzeid
Middle East Fertility Society Journal, June 2013. 18(2):67-73. - Outpatient management of severe ovarian hyperstimulation syndrome (OHSS) with Placement of Pigtail Catheter
M Abuzeid, H Warda, S Joseph, MG Corrado, Y Abuzeid, M Ashraf, B Rizk
Facts, Views, and Vision in OBGYN, 2014, 6(1):31-37. - Recurrence of endometriosis after hysterectomy
B Rizk, AS Fisher, HA Lotfy, R Turki, HA Zahed, R Malik, CP Holliday, A Glass, H Fishel, MY Solliman, D Herrera
Facts, Views, and Vision in OBGYN, 2014, 6(4):219-227. - Surgery for endometriosis-associated infertility: do we exaggerate the magnitude of effect?
B Rizk, R Turki, H Lotfy, S Ranganathan, H Zahed, AR Freeman, Z Shilbayeh, M Sassy, M Shalaby, R Malik
Facts, Views, and Vision in OBGYN, 2015:7(2):109-118. - Resection of Uterine Septum Using the MyoSure Tissue Removal System
Rizwan Malik, Saoud Rizwan, B Rizk
Journal Minimally Invasive Gynecology, 2015 Nov-Dec;22(6S):S123. - The effectiveness of hespan in reducing the incidence of severe hyperstimulation syndrome in polycystic ovarian disease patients.
Abdel Aziz A, Joseph S, Salem W, Abed S, Rizk B, Abuzeid M.
Middle East Fertility Society J. 2016; Sep:21(3):189-93. - Antenatal Perineal Massage Improves Women’s Experience of Childbirth and Postpartum Recovery: A Review to Facilitate Provider and Patient Education on the Technique.
Ellington JE, Rizk B, Criso S
J Womens Health, Issues & Care. 2017; Apr:6(2):1-7.
