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Huntington Reproductive Center - Blogs

The HRC Fertility Blog is a resource for patients and those seeking infertility related issues and articles. Check back often or subscribe to this blog as it is changed weekly by the HRC staff.

Clomid is the First Line of Fertility Treatment

Dr. Michele Evans, FACOG

Hi, I am Dr. Michele Evans.  I have been practicing at HRC Fertility for seven years, and have been a women’s health specialist for over 15 years.  In my practice, I see women and couples for fertility treatment, fertility preservation, recurrent miscarriage and hormone abnormalities.  One of our most common and simple fertility treatments uses a medication called Clomiphene citrate (Clomid).

Clomid has been used for the treatment of infertility for over 40 years.  It was first synthesized in 1956, and was approved by the United States Food and Drug Administration (FDA) in 1967.

Clomid is primarily used for women who do not ovulate predictably or who do not ovulate at all.  It is a selective estrogen receptor modulator (SERM) that “tricks” a woman’s body into thinking it is low in estrogen so that she releases more hormone (follicle stimulating hormone or FSH) to make an egg grow and release.  Approximately 80% of women who did not ovulate previously will ovulate with Clomid treatment.  Clomid is also used in combination with intrauterine insemination (IUI) to improve pregnancy rates in couples with unexplained infertility.

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