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  1. HRC Anonymous User
  2. IVF
  3. Tuesday, 26 February 2013
  4.  Subscribe via email
Dear Dr,

From your experience, how well have women with theC677T homozygous mutation, done treating a pregnancy with just high levels of folic acid and baby aspirin?

Now a days many doctors oppose using Lovenox especially in my case. I've had a normal pregnancy(fresh cycle) and 3 unsuccessful FET pregnancies(subchorionic bleed, blighted and chemical)before diagnosis. All frozen embryos were from my late 20s. IVFdue to male factor. High risk OB blames losses to the FET process rather than the Mthfr.

Thank you!
Responses (1)
DrTourgeman Accepted Answer Pending Moderation
Hello - Indeed most patients with MTHFR gene mutations will be appropriately treated with Folic acid, Vits B6 and B12; treated patients tend to do very well. There does not appear to be any data to support lovenox or even baby aspirin. It is unlikely that the losses are due to frozen transfers.

Best,
David Tourgeman, MD
  1. more than a month ago
  2. IVF
  3. # 1
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